Cellosaurus logo
expasy logo

Cellosaurus BJAB-HR1K (CVCL_B6UK)

[Text version]
Cell line name BJAB-HR1K
Synonyms BJAB/HR1K
Accession CVCL_B6UK
Resource Identification Initiative To cite this cell line use: BJAB-HR1K (RRID:CVCL_B6UK)
Comments Population: African; Kenyan.
Virology: EBV-negative cell line infected with EBV from P3HR-1 cell line (Cellosaurus=CVCL_2676) (PubMed=175026).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Groin; UBERON=UBERON_0008337.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5711 (BJAB)
Children:
CVCL_E4B1 (BJAB-HR1K-A5)CVCL_E4B2 (BJAB-HR1K-A7)CVCL_E4AZ (BJAB-HR1K-B1)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=62724; DOI=10.1002/ijc.2910180513
Klein G., Zeuthen J., Terasaki P.I., Billing R.J., Honig R., Jondal M., Westman A., Clements G.B.
Inducibility of the Epstein-Barr virus (EBV) cycle and surface marker properties of EBV-negative lymphoma lines and their in vitro EBV-converted sublines.
Int. J. Cancer 18:639-652(1976)

PubMed=175026; DOI=10.1002/ijc.2910170203
Fresen K.-O., zur Hausen H.
Establishment of EBNA-expressing cell lines by infection of Epstein-Barr virus (EBV)-genome-negative human lymphoma cells with different EBV strains.
Int. J. Cancer 17:161-166(1976)

PubMed=191406; DOI=10.1002/ijc.2910190306
Fresen K.-O., Merkt B., Bornkamm G.-W., zur Hausen H.
Heterogeneity of Epstein-Barr virus originating from P3HR-1 cells. I Studies on EBNA induction.
Int. J. Cancer 19:317-323(1977)

PubMed=196397; DOI=10.1016/0042-6822(77)90065-4
zur Hausen H., Fresen K.-O.
Heterogeneity of Epstein-Barr virus. II. Induction of early antigens (EA) by complementation.
Virology 81:138-143(1977)

PubMed=8449221; DOI=10.1002/eji.1830230325
Uchanska-Ziegler B., Noessner E., Schenk A., Ziegler A., Schendel D.J.
Soluble T cell receptor-like properties of an HLA-B35-specific monoclonal antibody (TU165).
Eur. J. Immunol. 23:734-738(1993)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6UK
Encyclopedic resources Wikidata; Q111732960
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number8