ID   iKLF1.1
AC   CVCL_B6RA
DR   Wikidata; Q111733491
RX   PubMed=28026072;
CC   Characteristics: Using ZFN a CAG-HA-KLF1-ERT2 construct has been inserted at the AAVS1 safe harbor locus so as to allow temporally controlled activation during macrophage differentiation.
CC   Genetic integration: Method=ZFN; Gene=HGNC; 3467; ESR1 (Note=Ligand-binding domain with p.Gly400Val, p.Met543Ala and p.Leu544Ala = ET[T2]).
CC   Genetic integration: Method=ZFN; Gene=HGNC; 6345; KLF1.
CC   Genetic integration: Method=ZFN; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_UL47 ! SFCi55
SX   Female
CA   Induced pluripotent stem cell
DT   Created: 17-03-22; Last updated: 10-09-24; Version: 5
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RX   PubMed=28026072; DOI=10.1002/stem.2562; PMCID=PMC5396323;
RA   Yang C.-T., Ma R., Axton R.A., Jackson M., Taylor A.H., Fidanza A.,
RA   Marenah L., Frayne J., Mountford J.C., Forrester L.M.;
RT   "Activation of KLF1 enhances the differentiation and maturation of red
RT   blood cells from human pluripotent stem cells.";
RL   Stem Cells 35:886-897(2017).
//