ID   WM164 VDR KO
AC   CVCL_B6Q1
SY   VDR KO WM164
DR   cancercelllines; CVCL_B6Q1
DR   Wikidata; Q112041937
RX   PubMed=34206371;
CC   Population: Caucasian.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:12679; VDR.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Arm, skin; UBERON=UBERON_0002427.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_7928 ! WM164
SX   Male
AG   22Y
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 19-12-24; Version: 6
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RX   PubMed=34206371; DOI=10.3390/cancers13133111; PMCID=PMC8269360;
RA   Podgorska E., Kim T.-K., Janjetovic Z., Urbanska K., Tuckey R.C.,
RA   Bae S., Slominski A.T.;
RT   "Knocking out the vitamin D receptor enhances malignancy and decreases
RT   responsiveness to vitamin D3 hydroxyderivatives in human melanoma
RT   cells.";
RL   Cancers (Basel) 13:3111.1-3111.15(2021).
//