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Cellosaurus TJU-UM001-tdTomato (CVCL_B6PZ)

[Text version]
Cell line name TJU-UM001-tdTomato
Synonyms UM001-tdTomato
Accession CVCL_B6PZ
Resource Identification Initiative To cite this cell line use: TJU-UM001-tdTomato (RRID:CVCL_B6PZ)
Comments Doubling time: ~72 hours (PubMed=26613897).
Genetic integration: Method=Transfection/transduction; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:4390; GNAQ; Simple; p.Gln209Pro (c.626A>C); ClinVar=VCV000375957; Zygosity=Heterozygous (from parent cell line).
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B6PW (TJU-UM001)
Category Cancer cell line
Publications

PubMed=26613897; DOI=10.1016/j.ajpath.2015.09.011; PMCID=PMC4715216
Ozaki S., Vuyyuru R., Kageyama K., Terai M., Ohara M., Cheng H.-Y., Manser T.L., Mastrangelo M.J., Aplin A.E., Sato T.
Establishment and characterization of orthotopic mouse models for human uveal melanoma hepatic colonization.
Am. J. Pathol. 186:43-56(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6PZ
Encyclopedic resources Wikidata; Q112041792
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number7