ID   mEERL95
AC   CVCL_B6JB
DR   Wikidata; Q112129253
RX   PubMed=29313973;
CC   Characteristics: Established from a tumor in a C57BL/6JRj mouse which was implanted with the parent cell line (PubMed=29313973).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Pharynx, oropharynx; UBERON=UBERON_0001729.
CC   Cell type: Epithelial cell; CL=CL_0000066.
CC   Breed/subspecies: C57BL/6.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_B6J3 ! mEERL
SX   Male
AG   6-8W
CA   Transformed cell line
DT   Created: 17-03-22; Last updated: 19-12-24; Version: 7
//
RX   PubMed=29313973; DOI=10.1002/ijc.31240;
RA   Mermod M., Hiou-Feige A., Bovay E., Roh V., Sponarova J.,
RA   Bongiovanni M., Vermeer D.W., Lee J.H., Petrova T.V., Rivals J.-P.,
RA   Monnier Y., Tolstonog G.V., Simon C.;
RT   "Mouse model of postsurgical primary tumor recurrence and regional
RT   lymph node metastasis progression in HPV-related head and neck
RT   cancer.";
RL   Int. J. Cancer 142:2518-2528(2018).
//