ID   MLM #5
AC   CVCL_B6J6
SY   MLM#5; mEERL lung metastasis clone 5
DR   GEO; GSM1687311
DR   GEO; GSM1687312
DR   GEO; GSM1687313
DR   GEO; GSM1687314
DR   Wikidata; Q112129335
RX   PubMed=27013584;
CC   Characteristics: Established from lung tumors obtained after injection of the parent cell line into a mouse that was then treated with cisplatin/radiation therapy (CRT) (PubMed=27013584).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Pharynx, oropharynx; UBERON=UBERON_0001729.
CC   Cell type: Epithelial cell; CL=CL_0000066.
CC   Breed/subspecies: C57BL/6.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_B6J3 ! mEERL
SX   Male
AG   6-8W
CA   Transformed cell line
DT   Created: 17-03-22; Last updated: 19-12-24; Version: 7
//
RX   PubMed=27013584; DOI=10.18632/oncotarget.8254; PMCID=PMC5029694;
RA   Vermeer D.W., Coppock J.D., Zeng E.-L., Lee K.M., Spanos W.C.,
RA   Onken M.D., Uppaluri R., Lee J.H., Vermeer P.D.;
RT   "Metastatic model of HPV+ oropharyngeal squamous cell carcinoma
RT   demonstrates heterogeneity in tumor metastasis.";
RL   Oncotarget 7:24194-24207(2016).
//