ID   HepZ
AC   CVCL_B6FC
DR   Wikidata; Q111733393
RX   Patent=US6046050;
RX   PubMed=10415582;
RX   PubMed=10699872;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ); ACC-2302.
CC   Characteristics: Transfected with albumin-promoter regulated antisense constructs against RB1 and TP53.
CC   Transfected with: HGNC; 1582; CCND1.
CC   Transfected with: HGNC; 3113; E2F1.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Hepatocyte; CL=CL_0000182.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Transformed cell line
DT   Created: 17-03-22; Last updated: 29-06-23; Version: 4
//
RX   Patent=US6046050;
RA   Strauss M., Kirillowa I.;
RT   "Human liver cell line.";
RL   Patent number US6046050, 04-Apr-2000.
//
RX   PubMed=10415582; DOI=10.1111/j.1749-6632.1999.tb08518.x;
RA   Werner A., Duvar S., Muthing J., Buntemeyer H., Kahmann U.,
RA   Lunsdorf H., Lehmann J.;
RT   "Cultivation and characterization of a new immortalized human
RT   hepatocyte cell line, HepZ, for use in an artificial liver support
RT   system.";
RL   Ann. N. Y. Acad. Sci. 875:364-368(1999).
//
RX   PubMed=10699872; DOI=10.1002/(SICI)1097-0290(20000405)68:1<59::AID-BIT7>3.0.CO;2-N;
RA   Werner A., Duvar S., Muthing J., Buntemeyer H., Lunsdorf H.,
RA   Strauss M., Lehmann J.;
RT   "Cultivation of immortalized human hepatocytes HepZ on macroporous
RT   CultiSpher G microcarriers.";
RL   Biotechnol. Bioeng. 68:59-70(2000).
//