Cellosaurus OUMS-29/TK (CVCL_B6EK)
| Cell line name | OUMS-29/TK |
|---|---|
| Synonyms | OUMS-29/thymidine kinase |
| Accession | CVCL_B6EK |
| Resource Identification Initiative | To cite this cell line use: OUMS-29/TK (RRID:CVCL_B6EK) |
| Comments | Population: Japanese. Characteristics: The introduction of HSV-1 TK gene makes the cell line 100x as sensitive to ganciclovir (GCV) compared with unmodified cells. This suicide gene can be used as a safeguard in the use of this cell line in hybrid artificial liver (PubMed=11575821). Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK. Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo). Derived from site: In situ; Fetal liver; UBERON=UBERON_0002107. Cell type: Hepatocyte; CL=CL_0000182. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_9130 (OUMS-29) |
| Sex of cell | Male |
| Age at sampling | 21FW |
| Category | Transformed cell line |
| Publications | PubMed=11575821; DOI=10.1097/00002480-200109000-00016 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q112129481 |
| Entry history | |
| Entry creation | 17-Mar-2022 |
| Last entry update | 10-Apr-2025 |
| Version number | 7 |