Cellosaurus TMhep48 (CVCL_B6DQ)
| Cell line name | TMhep48 |
|---|---|
| Synonyms | TMHepTG3960 x 2984 x 4912 48; TMHepTG3960 x 2984 x 4912 line 48 |
| Accession | CVCL_B6DQ |
| Resource Identification Initiative | To cite this cell line use: TMhep48 (RRID:CVCL_B6DQ) |
| Comments | Group: Patented cell line. Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-989. Characteristics: Established from a triple transgenic mice that contains 1) a human SERPINA1 promoter driving the expression of a mouse Myc as well as a second SERPINA1 promoter in front of a full copy of SERPINA1, 2) a human SERPINA1 promoter driving the expression of SV40 T-antigen and 3) a human F9 promoter driving the expression of F9 (PubMed=1369183). Genetic integration: Method=Transgenic mouse; Gene=HGNC; HGNC:3551; F9. Genetic integration: Method=Transgenic mouse; Gene=HGNC; HGNC:8941; SERPINA1. Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:97250; Myc. Transformant: Myc. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Liver; UBERON=UBERON_0002107. |
| Disease | Hepatocellular carcinoma of the mouse (NCIt: C38756) |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 x SJL transgenic TG3960 x TG2984 x TG4912. |
| Category | Cancer cell line |
| Publications | PubMed=1369183; DOI=10.1007/BF02521733 Patent=US5814716 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q112041798 |
| Entry history | |
| Entry creation | 17-Mar-2022 |
| Last entry update | 10-Apr-2025 |
| Version number | 7 |