Cellosaurus cell line C2BBe1 MRP3 KO (CVCL

Cross-references
Cell line name	C2BBe1 MRP3 KO
Synonyms	Caco-2 MRP3 Knockout Cell Line; C2BBe1 MRP3 Knockout Cell Line
Accession	CVCL_B6A2
Resource Identification Initiative	To cite this cell line use: C2BBe1 MRP3 KO (RRID:CVCL_B6A2)
Comments	Population: Caucasian. Knockout cell: Method=ZFN; HGNC; HGNC:54; ABCC3. Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1367Ter (c.4099C>T); ClinVar=VCV000376060; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly245Ala (c.734G>C); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Asp351His (c.1051G>C); ClinVar=VCV000375998; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu204Ter (c.610G>T); ClinVar=VCV000977783; Zygosity=Homozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1096 (C2BBe1)
Sex of cell	Male
Age at sampling	72Y
Category	Cancer cell line
Cell line collections (Providers)	Sigma-Aldrich; MTOX1093 Sigma-Aldrich; MTOX1093P24
Cell line databases/resources	cancercelllines; CVCL_B6A2
Encyclopedic resources	Wikidata; Q111733043
Entry history
Entry creation	17-Mar-2022
Last entry update	19-Dec-2024
Version number	8