Cellosaurus NK92-41BB (CVCL_B5ZF)
| Cell line name | NK92-41BB |
|---|---|
| Accession | CVCL_B5ZF |
| Resource Identification Initiative | To cite this cell line use: NK92-41BB (RRID:CVCL_B5ZF) |
| Comments | Population: Caucasian. Characteristics: Transfected with the CD16-CAR construct that consist of the signal peptide, the FCGR3/CD16A extracellular domain, the CD8A extracellular domain, the CD28 TM and co-activation domains, the 4-1BB co-activation domain and finally the CD247/CD3Z signaling domain. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3619; FCGR3A (Note=Extracellular domain). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: Natural killer cell; CL=CL_0000623. |
| Disease | Natural killer cell lymphoblastic leukemia/lymphoma (NCIt: C82217) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_2142 (NK-92) |
| Sex of cell | Male |
| Age at sampling | 50Y |
| Category | Cancer cell line |
| Publications | PubMed=34349345; DOI=10.1007/s10616-021-00476-1; PMCID=PMC8319282 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q112129460 |
| Entry history | |
| Entry creation | 17-Mar-2022 |
| Last entry update | 19-Dec-2024 |
| Version number | 7 |