ID   V79MZh1B1
AC   CVCL_B5WP
SY   V79MZ-h1B1; V79 cell clone #6
DR   Wikidata; Q112041909
RX   PubMed=9625737;
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 2597; CYP1B1.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 9208; POR.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4V36 ! V79MZ
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 17-03-22; Last updated: 10-09-24; Version: 5
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RX   PubMed=9625737; DOI=10.1021/tx970236p;
RA   Luch A., Coffing S.L., Tang Y.M., Schneider A., Soballa V., Greim H.,
RA   Jefcoate C.R., Seidel A., Greenlee W.F., Baird W.M., Doehmer J.;
RT   "Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster
RT   cells and metabolically catalyzed DNA adduct formation of
RT   dibenzo[a,l]pyrene.";
RL   Chem. Res. Toxicol. 11:686-695(1998).
//