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Cellosaurus AG27609 (CVCL_B5PR)

[Text version]
Cell line name AG27609
Synonyms AG27609*B
Accession CVCL_B5PR
Resource Identification Initiative To cite this cell line use: AG27609 (RRID:CVCL_B5PR)
Comments Population: Caucasian.
Derived from site: In situ; Thigh, skin; UBERON=UBERON_0004262.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:613; APOE; Simple; p.Cys130Arg (c.388T>C); ClinVar=VCV000017864; Zygosity=Homozygous; Note=ApoE4 allele (PubMed=30699343).
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4M37 (AG10788)
Sex of cell Female
Age at sampling 87Y
Category Induced pluripotent stem cell
Publications

PubMed=30699343; DOI=10.1016/j.celrep.2019.01.023; PMCID=PMC6386196
Meyer K., Feldman H.M., Lu T., Drake D., Lim E.T., Ling K.-H., Bishop N.A., Pan Y., Seo J., Lin Y.-T., Su S.C., Church G.M., Tsai L.-H., Yankner B.A.
REST and neural gene network dysregulation in iPSC models of Alzheimer's disease.
Cell Rep. 26:1112-1127.e9(2019)

Cross-references
Cell line collections (Providers) Coriell; AG27609
Encyclopedic resources Wikidata; Q111732884
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number5