Cellosaurus logo
expasy logo

Cellosaurus 88.6/D800-B (CVCL_B5P1)

[Text version]
Cell line name 88.6/D800-B
Synonyms D800-B
Accession CVCL_B5P1
Resource Identification Initiative To cite this cell line use: 88.6/D800-B (RRID:CVCL_B5P1)
Comments Knockout cell: Method=KO mouse; MGI; MGI:97570; Abcb1a.
Knockout cell: Method=KO mouse; MGI; MGI:97568; Abcb1b.
Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Sequence variations
  • Mutation; MGI; MGI:1347061; Abcg2; Simple; p.Arg482Ser (c.1446G>T); Zygosity=Homozygous (PubMed=11956086).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_B5NX (88.6)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=11956086
Allen J.D., Jackson S.C., Schinkel A.H.
A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for doxorubicin resistance.
Cancer Res. 62:2294-2299(2002)

Cross-references
Encyclopedic resources Wikidata; Q111732824
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number5