ID   KOT52/D800
AC   CVCL_B5NW
SY   D800
DR   Wikidata; Q111733559
RX   PubMed=11956086;
CC   Knockout cell: Method=KO mouse; MGI; MGI:97570; Abcb1a.
CC   Knockout cell: Method=KO mouse; MGI; MGI:97568; Abcb1b.
CC   Knockout cell: Method=KO mouse; MGI; MGI:102676; Abcc1.
CC   Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
CC   Sequence variation: Mutation; MGI; MGI:1347061; Abcg2; Simple; p.Arg482Met (c.1445G>T); Zygosity=Heterozygous (PubMed=11956086).
CC   Derived from site: In situ; Ear, skin; UBERON=UBERON_0001459.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_B5NT ! KOT52
SX   Sex unspecified
CA   Spontaneously immortalized cell line
DT   Created: 17-03-22; Last updated: 19-12-24; Version: 5
//
RX   PubMed=11956086;
RA   Allen J.D., Jackson S.C., Schinkel A.H.;
RT   "A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in
RT   mouse cell lines selected for doxorubicin resistance.";
RL   Cancer Res. 62:2294-2299(2002).
//