Cellosaurus 1C11 [Mouse teratocarcinoma] (CVCL_B5MU)
| Cell line name | 1C11 [Mouse teratocarcinoma] |
|---|---|
| Accession | CVCL_B5MU |
| Resource Identification Initiative | To cite this cell line use: 1C11 [Mouse teratocarcinoma] (RRID:CVCL_B5MU) |
| Comments | Characteristics: Tumorigenic in syngeneic mice (PubMed=2155426). Characteristics: Presents two states: an immature phenotype (1C11 precursor) and a more differentiated state (1C11*). After induction by Bt2cAMP and cyclohexanecarboxylate, 1C11* cells extend neurites and express neural markers such as NCAM1, synaptophysin and [Met5]enkephalin in >95% of the clonal population (PubMed=2155426). Doubling time: 20 hours (PubMed=2155426). Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). |
| Disease | Mouse teratocarcinoma (NCIt: C129859) |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: 129/Sv. |
| Hierarchy | Parent: CVCL_B5MT (F9K4b2) |
| Sex of cell | Male |
| Age at sampling | Embryo |
| Category | Cancer cell line |
| Publications | PubMed=2155426; DOI=10.1073/pnas.87.5.1922; PMCID=PMC53596 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q111732620 |
| Entry history | |
| Entry creation | 17-Mar-2022 |
| Last entry update | 10-Sep-2024 |
| Version number | 4 |