Cellosaurus logo
expasy logo

Cellosaurus XWHNi001-A (CVCL_B5GR)

[Text version]
Cell line name XWHNi001-A
Accession CVCL_B5GR
Resource Identification Initiative To cite this cell line use: XWHNi001-A (RRID:CVCL_B5GR)
Comments From: Department of Neurology, Xuan Wu Hospital; Beijing; China.
Population: Chinese.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 620; APP; Simple; p.Val717Ile (c.2149G>A); ClinVar=VCV000018088; Zygosity=Homozygous (PubMed=35149456).
Disease Familial Alzheimer's disease, type 1 (NCIt: C146894)
Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 58Y
Category Induced pluripotent stem cell
STR profile Source(s): PubMed=35149456

Markers:
AmelogeninX
CSF1PO12
D2S44111
D2S133823,24
D3S135816
D5S81811
D6S104317,19
D7S82011,13
D8S117912,13
D12S39115,18
D13S3178,11
D16S5399
D18S5115,22
D19S43314,15.2
D21S1129,30
FGA20,23
Penta D6,9
Penta E12,20
TH019
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=35149456; DOI=10.1016/j.scr.2022.102690
Wei C.-B., Lu X.-L., Zou Q., Gong S.-T., Chen Y.-F., Lyu J.-H., Jia J.-P.
Generation and characterization of a human induced pluripotent stem cell line (XWHNi001-A) derived from an Alzheimer's disease patient with mutation in the APP gene.
Stem Cell Res. 60:102690-102690(2022)

Cross-references
Cell line databases/resources hPSCreg; XWHNi001-A
Biological sample resources BioSamples; SAMEA10329923
Encyclopedic resources Wikidata; Q110434432
Entry history
Entry creation16-Dec-2021
Last entry update29-Jun-2023
Version number4