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Cellosaurus 29c (CVCL_B522)

[Text version]
Cell line name 29c
Synonyms A29c; 29c-ALS
Accession CVCL_B522
Resource Identification Initiative To cite this cell line use: 29c (RRID:CVCL_B522)
Comments From: Harvard University; Boston; USA.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 11179; SOD1; Simple; p.Leu145Phe (c.435G>C) (L144F); ClinVar=VCV000586637; Zygosity=Unspecified (PubMed=18669821).
Disease Amyotrophic lateral sclerosis 1 (NCIt: C168749)
Amyotrophic lateral sclerosis (ORDO: Orphanet_803)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_8999 ! 29a
CVCL_9000 ! 29b
CVCL_9001 ! 29d
CVCL_9002 ! 29e
Sex of cell Female
Age at sampling 82Y
Category Induced pluripotent stem cell
Publications

PubMed=18669821; DOI=10.1126/science.1158799
Dimos J.T., Rodolfa K.T., Niakan K.K., Weisenthal L.M., Mitsumoto H., Chung W.K., Croft G.F., Saphier G., Leibel R.L., Goland R.S., Wichterle H., Henderson C.E., Eggan K.C.
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons.
Science 321:1218-1221(2008)

Cross-references
Cell line databases/resources SKIP; SKIP004435
Encyclopedic resources Wikidata; Q54584272
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number17