Cellosaurus cell line GM2493 (CVCL

Cross-references
Cell line name	GM2493
Accession	CVCL_B4G5
Resource Identification Initiative	To cite this cell line use: GM2493 (RRID:CVCL_B4G5)
Comments	Characteristics: Early passage culture. Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (PubMed=14961077).
Disease	Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=14961077; DOI=10.1038/sj.onc.1207244 Wang Y.-L., Zhu S.-J., Cloughesy T.F., Liau L.M., Mischel P.S. p53 disruption profoundly alters the response of human glioblastoma cells to DNA topoisomerase I inhibition. Oncogene 23:1283-1290(2004)
Cell line databases/resources	cancercelllines; CVCL_B4G5
Encyclopedic resources	Wikidata; Q110432828
Polymorphism and mutation databases	IARC_TP53; 20806
Entry history
Entry creation	16-Dec-2021
Last entry update	19-Dec-2024
Version number	6