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Cellosaurus IGR-39D (CVCL_B491)

[Text version]
Cell line name IGR-39D
Synonyms IGR 39D; IGR39D
Accession CVCL_B491
Resource Identification Initiative To cite this cell line use: IGR-39D (RRID:CVCL_B491)
Comments Population: Caucasian.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys229Tyrfs*10 (c.686_687delGT); ClinVar=VCV000863486; Zygosity=Unspecified (PubMed=10070891).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2076 (IGR-39)
Sex of cell Male
Age at sampling 26Y
Category Cancer cell line
Publications

PubMed=3402430; DOI=10.1002/j.1460-2075.1988.tb02909.x; PMCID=PMC454430
Versteeg R., Noordermeer I.A., Kruse-Wolters M., Ruiter D.J., Schrier P.I.
c-myc down-regulates class I HLA expression in human melanomas.
EMBO J. 7:1023-1029(1988)

PubMed=10070891; DOI=10.1038/sj.bjc.6690147; PMCID=PMC2362648
Zerp S.F., van Elsas A., Peltenburg L.T.C., Schrier P.I.
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis.
Br. J. Cancer 79:921-926(1999)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B491
Encyclopedic resources Wikidata; Q54897369
Polymorphism and mutation databases Cosmic; 1418459
IARC_TP53; 10955
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number18