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Cellosaurus LNCaP-34 (CVCL_B414)

[Text version]
Cell line name LNCaP-34
Accession CVCL_B414
Resource Identification Initiative To cite this cell line use: LNCaP-34 (RRID:CVCL_B414)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 5155; HPN.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1379 (LNCaP clone FGC)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=16908524; DOI=10.1074/jbc.M605440200
Moran P., Li W., Fan B., Vij R., Eigenbrot C., Kirchhofer D.
Pro-urokinase-type plasminogen activator is a substrate for hepsin.
J. Biol. Chem. 281:30439-30446(2006)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B414
Anatomy/cell type resources BTO; BTO:0005045
Encyclopedic resources Wikidata; Q54902829
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number20