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Cellosaurus HMB-50 (CVCL_B3XS)

[Text version]
Cell line name HMB-50
Synonyms HMB 50; HMB50
Accession CVCL_B3XS
Resource Identification Initiative To cite this cell line use: HMB-50 (RRID:CVCL_B3XS)
Comments Monoclonal antibody isotype: IgG2a.
Monoclonal antibody target: UniProtKB; P40967; Human PMEL.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category Hybridoma
Publications

PubMed=3518473; PMCID=PMC1888307
Gown A.M., Vogel A.M., Hoak D., Gough F., McNutt M.A.
Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes.
Am. J. Pathol. 123:195-203(1986)

PubMed=3766867; DOI=10.1016/0002-9610(86)90308-9
Esclamado R.M., Gown A.M., Vogel A.M.
Unique proteins defined by monoclonal antibodies specific for human melanoma. Some potential clinical applications.
Am. J. Surg. 152:376-385(1986)

PubMed=3342407
Vogel A.M., Esclamado R.M.
Identification of a secreted Mr 95,000 glycoprotein in human melanocytes and melanomas by a melanocyte specific monoclonal antibody.
Cancer Res. 48:1286-1294(1988)

PubMed=7504884; PMCID=PMC1887279
Adema G.J., de Boer A.J., van 't Hullenaar R., Denijn M., Ruiter D.J., Vogel A.M., Figdor C.G.
Melanocyte lineage-specific antigens recognized by monoclonal antibodies NKI-beteb, HMB-50, and HMB-45 are encoded by a single cDNA.
Am. J. Pathol. 143:1579-1585(1993)

PubMed=8624261; DOI=10.1038/bjc.1996.202; PMCID=PMC2074403
Adema G.J., Bakker A.B.H., de Boer A.J., Hohenstein P., Figdor C.G.
pMel17 is recognised by monoclonal antibodies NKI-beteb, HMB-45 and HMB-50 and by anti-melanoma CTL.
Br. J. Cancer 73:1044-1048(1996)

Cross-references
Encyclopedic resources Wikidata; Q110432899
Entry history
Entry creation16-Dec-2021
Last entry update21-Mar-2023
Version number3