Cellosaurus cell line NCC-CCS1-X4-C1 (CVCL

Cellosaurus NCC-CCS1-X4-C1 (CVCL_B3TR)

[Text version]

Cell line name

NCC-CCS1-X4-C1

Synonyms

NCCCCS1X4C1

Accession

CVCL_B3TR

Resource Identification Initiative

To cite this cell line use: NCC-CCS1-X4-C1 (RRID:CVCL_B3TR)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: NCC sarcoma cell line panel.
Population: Japanese.
Characteristics: Established from a fourth generation xenograft established by subcutaneous injection in female NOD/Shi-scid IL-2Rgammanull mice.
Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo T.).
Doubling time: 17 hours (PubMed=29197033).
Omics: Deep proteome analysis.
Derived from site: Metastatic; Left thigh, hypodermis; UBERON=UBERON_0000376+UBERON_0002072.

Sequence variations

Gene fusion; HGNC; 783; ATF1 + HGNC; 3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF (PubMed=29197033).

Disease

Clear cell sarcoma of soft tissue (NCIt: C3745)
Soft tissue sarcoma (ORDO: Orphanet_3394)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_B3TS ! NCC-CCS1B-C1
CVCL_B3TT ! NCC-CCS1B-X2-C1

Sex of cell

Female

Age at sampling

43Y

Category

Cancer cell line

STR profile

Source(s): PubMed=29197033

Markers:

Amelogenin	X
CSF1PO	10
D5S818	11
D7S820	11,12
D13S317	8
D16S539	11
D21S11	30,31
TH01	6
TPOX	11
vWA	15,16

Web pages

https://en.cellline.jp/product/ncc-ccs1-x4-c1/

Publications

PubMed=29197033; DOI=10.1007/s11626-017-0207-5
Sakumoto M., Oyama R., Takahashi M., Takai Y., Kito F., Shiozawa K., Qiao Z.-W., Endo M., Yoshida A., Kawai A., Kondo T.
Establishment and proteomic characterization of patient-derived clear cell sarcoma xenografts and cell lines.
In Vitro Cell. Dev. Biol. Anim. 54:163-176(2018)

Cross-references

Cell line databases/resources

DepMap; ACH-002793

Encyclopedic resources

Wikidata; Q110433080

Entry history

Entry creation

16-Dec-2021

Last entry update

30-Jan-2024

Version number