Cellosaurus cell line 4T1.3 (CVCL

Cross-references
Cell line name	4T1.3
Accession	CVCL_B3QZ
Resource Identification Initiative	To cite this cell line use: 4T1.3 (RRID:CVCL_B3QZ)
Comments	Characteristics: Metastasizes with high frequency to bone upon orthotopic injection into the mammary fat pad of immunocompetent female BALB/c mice (PubMed=27177471). Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG). Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease	Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: BALB/cfC3H.
Hierarchy	Parent: CVCL_0125 (4T1)
Sex of cell	Female
Category	Cancer cell line
Publications	PubMed=27177471; DOI=10.1016/j.canlet.2016.05.005 Sasaki S.-i., Baba T., Nishimura T., Hayakawa Y., Hashimoto S.-i., Gotoh N., Mukaida N. Essential roles of the interaction between cancer cell-derived chemokine, CCL4, and intra-bone CCR5-expressing fibroblasts in breast cancer bone metastasis. Cancer Lett. 378:23-32(2016) PubMed=34632664; DOI=10.1111/cas.15150; PMCID=PMC8645723 Sasaki S.-i., Zhang D., Iwabuchi S., Tanabe Y., Hashimoto S.-i., Yamauchi A., Hayashi K., Tsuchiya H., Hayakawa Y., Baba T., Mukaida N. Crucial contribution of GPR56/ADGRG1, expressed by breast cancer cells, to bone metastasis formation. Cancer Sci. 112:4883-4893(2021)
Encyclopedic resources	Wikidata; Q110429789
Entry history
Entry creation	16-Dec-2021
Last entry update	19-Dec-2024
Version number	5