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Cellosaurus Dnmt1(Y495C)-1 (CVCL_B3PW)

[Text version]
Cell line name Dnmt1(Y495C)-1
Synonyms Dnmt1Y495C-1
Accession CVCL_B3PW
Resource Identification Initiative To cite this cell line use: Dnmt1(Y495C)-1 (RRID:CVCL_B3PW)
Comments From: Birla Institute of Technology and Science Pilani, Hyderabad Campus; Hyderabad; India.
Genetic integration: Method=Homologous recombination; Gene=MGI; MGI:94912; Dnmt1 (Note=With p.Tyr501Cys; equivalent to human p.Tyr495Cys).
Genetic integration: Method=Homologous recombination; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 129X1/SvJ x 129S1/Sv-Oca2+Tyr+KitlSl-J.
Hierarchy Parent: CVCL_2167 (ES-R1)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=34634759; DOI=10.1016/j.scr.2021.102561
Choudhury S., Mohan K.N.
Generation of a transgenic mouse embryonic stem cell line expressing Dnmt1(Y495C) mutation associated with HSAN1E disorder.
Stem Cell Res. 56:102561-102561(2021)

Cross-references
Encyclopedic resources Wikidata; Q110432776
Entry history
Entry creation16-Dec-2021
Last entry update19-Dec-2024
Version number6