Cellosaurus cell line UOK353 (CVCL

Cross-references
Cell line name	UOK353
Accession	CVCL_B3PQ
Resource Identification Initiative	To cite this cell line use: UOK353 (RRID:CVCL_B3PQ)
Comments	Population: African American. Doubling time: ~72 hours (PubMed=32259323). Karyotypic information: 43,XX,-4,-9,-15,t(19;22)(p13.1;q11.2) (PubMed=32259323). Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg181His (c.542G>A); ClinVar=VCV000142320; Zygosity=Heterozygous (PubMed=32259323).
Disease	Kidney medullary carcinoma (NCIt: C7572) Renal medullary carcinoma (ORDO: Orphanet_319319)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	42Y
Category	Cancer cell line
Publications	PubMed=32259323; DOI=10.1002/gcc.22847; PMCID=PMC7383978 Wei D., Yang Y.-F., Ricketts C.J., Vocke C.D., Ball M.W., Sourbier C., Wangsa Zong D., Wangsa D., Guha R., Zhang X.-H., Wilson K.M., Chen L., Meltzer P.S., Ried T., Thomas C.J., Merino M.J., Linehan W.M. Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutic treatments. Genes Chromosomes Cancer 59:472-483(2020)
Cell line databases/resources	cancercelllines; CVCL_B3PQ
Encyclopedic resources	Wikidata; Q110433949
Entry history
Entry creation	16-Dec-2021
Last entry update	19-Dec-2024
Version number	6