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Cellosaurus HeLa-ACE2-TMPRSS2 (CVCL_B3LV)

[Text version]
Cell line name HeLa-ACE2-TMPRSS2
Accession CVCL_B3LV
Resource Identification Initiative To cite this cell line use: HeLa-ACE2-TMPRSS2 (RRID:CVCL_B3LV)
Comments Population: African American.
Virology: Can be used to isolate human coronavirus NL63 (HCoV-NL63) (JCRB=JCRB1835).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 13557; ACE2.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11876; TMPRSS2.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1276 (HeLa 229)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1835

Markers:
AmelogeninX
CSF1PO10
D5S81811,12
D7S8208,12,13
D13S31713.3,14.3
D16S5399,10
TH017
TPOX8,12
vWA16,18,19

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Publications

PubMed=22496216; DOI=10.1128/JVI.00094-12; PMCID=PMC3393535
Kawase M., Shirato K., van der Hoek L., Taguchi F., Matsuyama S.
Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry.
J. Virol. 86:6537-6545(2012)

Cross-references
Cell line collections (Providers) JCRB; JCRB1835
Encyclopedic resources Wikidata; Q110432868
Entry history
Entry creation16-Dec-2021
Last entry update10-Sep-2024
Version number8