Cellosaurus logo
expasy logo

Cellosaurus Akata EBER(-) EBV (CVCL_B3LU)

[Text version]
Cell line name Akata EBER(-) EBV
Accession CVCL_B3LU
Resource Identification Initiative To cite this cell line use: Akata EBER(-) EBV (RRID:CVCL_B3LU)
Comments Population: Japanese.
Virology: EBV-negative cell line re-infected with recombinant EBV whose genome is KO for EBER1 and EBER2.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro190Leufs*57 (c.569delC); ClinVar=VCV000825904; Zygosity=Unspecified (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VN89 (Akata-EBV-N)
Children:
CVCL_B6R3 (Akata delta1 EBER2(+))CVCL_B3MK (Akata delta2 EBER1(+))CVCL_B3M6 (Akata EBER(+) EBV)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1832

Markers:
AmelogeninX
CSF1PO11
D5S81811,12
D7S82010,12
D13S3178,12
D16S53910,11
TH019
TPOX8,11
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=17686859; DOI=10.1128/JVI.00579-07; PMCID=PMC2045559
Wu Y., Maruo S., Yajima M., Kanda T., Takada K.
Epstein-Barr virus (EBV)-encoded RNA 2 (EBER2) but not EBER1 plays a critical role in EBV-induced B-cell growth transformation.
J. Virol. 81:11236-11245(2007)

Cross-references
Cell line collections (Providers) JCRB; JCRB1832
Cell line databases/resources cancercelllines; CVCL_B3LU
Encyclopedic resources Wikidata; Q110432576
Entry history
Entry creation16-Dec-2021
Last entry update19-Dec-2024
Version number9