AC   CVCL_B398
SY   Eskol
DR   Cosmic; 1809510
DR   Cosmic; 2690007
DR   GEO; GSM1374476
DR   Wikidata; Q54832831
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=1895754;
RX   PubMed=11060441;
RX   PubMed=11755467;
RX   PubMed=22653958;
CC   Problematic cell line: Possibly misclassified. It is not certain that this cell line originate from a hairy cell leukemia (PubMed=22653958).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C7402; Hairy cell leukemia
DI   ORDO; Orphanet_58017; Classic hairy cell leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   69Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 14
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001).
RX   PubMed=1895754; DOI=10.1016/0145-2126(91)90077-7;
RA   Harvey W., Srour E.F., Turner R., Carey R., Maze R., Starrett B.,
RA   Kanagala R., Pereira D., Merchant P., Taylor M.W., Jansen J.;
RT   "Characterization of a new cell line (ESKOL) resembling hairy-cell
RT   leukemia: a model for oncogene regulation and late B-cell
RT   differentiation.";
RL   Leuk. Res. 15:733-744(1991).
RX   PubMed=11060441; DOI=10.1159/000015656;
RA   Lindbjerg Andersen C., Ostergaard M., Nielsen B., Pedersen B.,
RA   Koch J.;
RT   "Characterization of three hairy cell leukemia- derived cell lines
RT   (ESKOL, JOK-1, and Hair-M) by multiplex-FISH, comparative genomic
RT   hybridization, FISH, PRINS, and dideoxyPRINS.";
RL   Cytogenet. Cell Genet. 90:30-39(2000).
RX   PubMed=11755467; DOI=10.1016/S0145-2126(01)00100-X;
RA   Khalaf W., Maina C., Byers J., Harvey W.;
RT   "Interferon-alpha 2b and vesnarinone influence levels of tumor
RT   necrosis factor-alpha, apoptosis, or interleukin 6 in ESKOL, a hairy
RT   cell leukemic cell line. A potential cytokine and oncogene
RT   relationship regulating apoptosis is suggested.";
RL   Leuk. Res. 26:169-177(2002).
RX   PubMed=22653958; DOI=10.1182/blood-2011-12-400374;
RA   Tiacci E., Pucciarini A., Bigerna B., Pettirossi V., Strozzini F.,
RA   Martelli M.P., Tabarrini A., Drexler H.G., Falini B.;
RT   "Absence of BRAF-V600E in the human cell lines BONNA-12, ESKOL, HAIR-M,
RT   and HC-1 questions their origin from hairy cell leukemia.";
RL   Blood 119:5332-5333(2012).