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Cellosaurus TL-1 (CVCL_B371)

[Text version]
Cell line name TL-1
Synonyms TL1
Accession CVCL_B371
Resource Identification Initiative To cite this cell line use: TL-1 (RRID:CVCL_B371)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Virology: EBV-negative.
Doubling time: ~36 hours (PubMed=2486610; PubMed=6268866).
Derived from site: In situ; Ileocecal lymph node; UBERON=UBERON_8480054.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:5362; ID3; Simple; p.Glu53Ter (c.157G>T); Zygosity=Heterozygous (DepMap=ACH-002055).
  • Mutation; HGNC; HGNC:7672; NCOR1; Simple; p.Ile1927fs (c.5779_5780delAT); Zygosity=Heterozygous (DepMap=ACH-002055).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr236Ser (c.707A>C); ClinVar=VCV000182966; Zygosity=Homozygous (DepMap=ACH-002055).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 10Y
Category Cancer cell line
STR profile Source(s): RCB=RCB1871; TKG=TKG 0607

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81810,12
D7S82010,12
D13S3178,11
D16S53912
TH016,7
TPOX9,11
vWA14,19

Run an STR similarity search on this cell line
Publications

PubMed=6268866
Hayashi Y., Matsumura Y., Nishihira T., Watanabe I., Ohi R., Kasai M., Kumagai K., Kamada N.
Burkitt's lymphoma cell line bearing surface IgA and negative for nuclear antigen of Epstein-Barr virus (EBNA).
Jpn. J. Exp. Med. 50:423-434(1980)

PubMed=2486610
Yaoita S., Ohoi R., Hayashi Y., Watanabe T.
Establishment and characterization of TL-1 cell line from a ileo-cecal Burkitt's lymphoma.
Hum. Cell 2:197-197(1989)

Cross-references
Cell line collections (Providers) RCB; RCB1871
TKG; TKG 0607
Cell line databases/resources CLO; CLO_0050020
DepMap; ACH-002055
Biological sample resources BioSample; SAMN03472078
Encyclopedic resources Wikidata; Q54972597
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number18