Cellosaurus cell line DF508 2 (CVCL

Cross-references
Cell line name	DF508 2
Synonyms	RC2 200
Accession	CVCL_B336
Resource Identification Initiative	To cite this cell line use: DF508 2 (RRID:CVCL_B336)
Comments	From: Boston University School of Medicine; Boston; USA. Population: Caucasian. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=20715179).
Disease	Cystic fibrosis (NCIt: C2975) Cystic fibrosis (ORDO: Orphanet_586)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_L744 (GM01012)
Sex of cell	Male
Age at sampling	8Y
Category	Induced pluripotent stem cell
Web pages	https://stemcellbank.bu.edu/Catalog/Item/Details/557
Publications	PubMed=20715179; DOI=10.1002/stem.495; PMCID=PMC3422663 Somers A., Jean J.-C., Sommer C.A., Omari A., Ford C.C., Mills J.A., Ying L., Gianotti-Sommer A., Jean J.M., Smith B.W., Lafyatis R., Demierre M.-F., Weiss D.J., French D.L., Gadue P., Murphy G.J., Mostoslavsky G., Kotton D.N. Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette. Stem Cells 28:1728-1740(2010)
Encyclopedic resources	Wikidata; Q54831025
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	22