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Cellosaurus S2/TXT (CVCL_B283)

[Text version]
Cell line name S2/TXT
Accession CVCL_B283
Resource Identification Initiative To cite this cell line use: S2/TXT (RRID:CVCL_B283)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_4672; Docetaxel anhydrous (Taxotere).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3172 (SUIT-2)
Sex of cell Male
Age at sampling 73Y
Category Cancer cell line
Publications

PubMed=11819752; DOI=10.3748/wjg.v7.i1.143; PMCID=PMC4688693
Liu B., Staren E., Iwamura T., Appert H., Howard J.
Effects of taxotere on invasive potential and multidrug resistance phenotype in pancreatic carcinoma cell line SUIT-2.
World J. Gastroenterol. 7:143-148(2001)

PubMed=11854916; DOI=10.3748/wjg.v7.i6.855; PMCID=PMC4695609
Liu B., Staren E., Iwamura T., Appert H., Howard J.
Taxotere resistance in SUIT. Taxotere resistance in pancreatic carcinoma cell line SUIT 2 and its sublines.
World J. Gastroenterol. 7:855-859(2001)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B283
Encyclopedic resources Wikidata; Q54951876
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number17