Cell line name |
S2-020 |
Synonyms |
SUIT2-020 |
Accession |
CVCL_B281 |
Resource Identification Initiative |
To cite this cell line use: S2-020 (RRID:CVCL_B281) |
Comments |
Population: Japanese. Doubling time: 24.8 hours (PubMed=1391733); 35.8 hours (PubMed=10027404). Derived from site: Metastatic; Liver; UBERON=UBERON_0002107. |
Sequence variations |
- Mutation; HGNC; 1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
|
Disease |
Pancreatic ductal adenocarcinoma (NCIt: C9120) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_3172 (SUIT-2) |
Sex of cell |
Male |
Age at sampling |
73Y |
Category |
Cancer cell line |
STR profile |
Source(s): TKG=TKG 0710
Markers: Run an STR similarity search on this cell line |
Publications | PubMed=1319859; DOI=10.1007/BF00133561 Taniguchi S., Iwamura T., Katsuki T. Correlation between spontaneous metastatic potential and type I collagenolytic activity in a human pancreatic cancer cell line (SUIT-2) and sublines. Clin. Exp. Metastasis 10:259-266(1992) PubMed=1391733; DOI=10.1111/j.1440-1746.1992.tb01030.x Iwamura T., Taniguchi S., Kitamura N., Yamanari H., Kojima A., Hidaka K., Setoguchi T., Katsuki T. Correlation between CA19-9 production in vitro and histological grades of differentiation in vivo in clones isolated from a human pancreatic cancer cell line (SUIT-2). J. Gastroenterol. Hepatol. 7:512-519(1992) PubMed=10027404; DOI=10.1016/S0002-9440(10)65292-3; PMCID=PMC1849991 Kataoka H., Uchino H., Iwamura T., Seiki M., Nabeshima K., Koono M. Enhanced tumor growth and invasiveness in vivo by a carboxyl-terminal fragment of alpha1-proteinase inhibitor generated by matrix metalloproteinases: a possible modulatory role in natural killer cytotoxicity. Am. J. Pathol. 154:457-468(1999) PubMed=11854916; DOI=10.3748/wjg.v7.i6.855; PMCID=PMC4695609 Liu B., Staren E., Iwamura T., Appert H., Howard J. Taxotere resistance in SUIT. Taxotere resistance in pancreatic carcinoma cell line SUIT 2 and its sublines. World J. Gastroenterol. 7:855-859(2001) |
Cross-references |
Cell line collections (Providers) |
TKG; TKG 0710
|
Cell line databases/resources |
cancercelllines; CVCL_B281
|
Encyclopedic resources |
Wikidata; Q54951841
|
Entry history |
Entry creation | 06-Jun-2012 |
Last entry update | 02-May-2024 |
Version number | 19 |
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