ID   S2-007
AC   CVCL_B279
SY   SUIT2-007; S2 007; Suit S2 007
DR   cancercelllines; CVCL_B279
DR   TKG; TKG 0708
DR   Wikidata; Q54951839
RX   PubMed=1319859;
RX   PubMed=1391733;
RX   PubMed=10027404;
RX   PubMed=11854916;
CC   Population: Japanese.
CC   Doubling time: 29.7 hours (PubMed=1391733); 41.8 hours (PubMed=10027404).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
ST   Source(s): TKG=TKG 0708
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 9,11
ST   D16S539: 9
ST   D5S818: 11,12
ST   D7S820: 9,11
ST   TH01: 6
ST   TPOX: 8,10
ST   vWA: 17
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3172 ! SUIT-2
SX   Male
AG   73Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 02-05-24; Version: 19
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RX   PubMed=1319859; DOI=10.1007/BF00133561;
RA   Taniguchi S., Iwamura T., Katsuki T.;
RT   "Correlation between spontaneous metastatic potential and type I
RT   collagenolytic activity in a human pancreatic cancer cell line (SUIT-2)
RT   and sublines.";
RL   Clin. Exp. Metastasis 10:259-266(1992).
//
RX   PubMed=1391733; DOI=10.1111/j.1440-1746.1992.tb01030.x;
RA   Iwamura T., Taniguchi S., Kitamura N., Yamanari H., Kojima A.,
RA   Hidaka K., Setoguchi T., Katsuki T.;
RT   "Correlation between CA19-9 production in vitro and histological
RT   grades of differentiation in vivo in clones isolated from a human
RT   pancreatic cancer cell line (SUIT-2).";
RL   J. Gastroenterol. Hepatol. 7:512-519(1992).
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RX   PubMed=10027404; DOI=10.1016/S0002-9440(10)65292-3;
RA   Kataoka H., Uchino H., Iwamura T., Seiki M., Nabeshima K., Koono M.;
RT   "Enhanced tumor growth and invasiveness in vivo by a carboxyl-terminal
RT   fragment of alpha1-proteinase inhibitor generated by matrix
RT   metalloproteinases: a possible modulatory role in natural killer
RT   cytotoxicity.";
RL   Am. J. Pathol. 154:457-468(1999).
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RX   PubMed=11854916; DOI=10.3748/wjg.v7.i6.855;
RA   Liu B., Staren E., Iwamura T., Appert H., Howard J.;
RT   "Taxotere resistance in SUIT. Taxotere resistance in pancreatic
RT   carcinoma cell line SUIT 2 and its sublines.";
RL   World J. Gastroenterol. 7:855-859(2001).
//