ID   KMC-1
AC   CVCL_B269
DR   EFO; EFO_0022353
DR   Wikidata; Q54900104
RX   CelloPub=CLPUB00275;
RX   PubMed=1332997;
RX   PubMed=7537711;
RX   PubMed=9178645;
RX   PubMed=35640676;
CC   Population: Japanese.
CC   Doubling time: 54 hours (Note=At 31th passage) (PubMed=1332997).
CC   HLA typing: A*24:02; B*40:06,52:01; C*08:01,12:02; DRB1*12:01,15:02 (PubMed=9178645).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C35417; Intrahepatic cholangiocarcinoma
DI   ORDO; Orphanet_70567; Cholangiocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-09-24; Version: 15
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RX   CelloPub=CLPUB00275;
RA   Zach S., Birgin E., Ruckert F.;
RT   "Primary cholangiocellular carcinoma cell lines.";
RL   J. Stem Cell Res. Transplant. 2:1013-1013(2015).
//
RX   PubMed=1332997; DOI=10.1016/0168-8278(92)90058-W;
RA   Iemura A., Maruiwa M., Yano H., Kojiro M.;
RT   "A new human cholangiocellular carcinoma cell line (KMC-1).";
RL   J. Hepatol. 15:288-298(1992).
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RX   PubMed=7537711; DOI=10.1002/hep.1840210510;
RA   Haramaki M., Yano H., Fukuda K., Momosaki S., Ogasawara S., Kojiro M.;
RT   "Expression of CD44 in human hepatocellular carcinoma cell lines.";
RL   Hepatology 21:1276-1284(1995).
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RX   PubMed=9178645; DOI=10.1006/cimm.1997.1108;
RA   Nakao M., Sata M., Saitsu H., Yutani S., Kawamoto M., Kojiro M.,
RA   Itoh K.;
RT   "CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with
RT   hepatocellular carcinoma.";
RL   Cell. Immunol. 177:176-181(1997).
//
RX   PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155;
RA   Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y.,
RA   Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S.,
RA   Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.;
RT   "Development and characterization of human primary cholangiocarcinoma
RT   cell lines.";
RL   Am. J. Pathol. 192:1200-1217(2022).
//