Cell line name |
PC/AA |
Synonyms |
AA |
Accession |
CVCL_B261 |
Resource Identification Initiative |
To cite this cell line use: PC/AA (RRID:CVCL_B261) |
Comments |
Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108. |
Sequence variations |
|
Disease |
Colorectal adenoma (NCIt: C5673) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Children:
|
Sex of cell |
Male |
Age at sampling |
34Y |
Category |
Cancer cell line |
Publications | PubMed=6746117; DOI=10.1002/ijc.2910340109 Paraskeva C., Buckle B.G., Sheer D., Wigley C.B. The isolation and characterization of colorectal epithelial cell lines at different stages in malignant transformation from familial polyposis coli patients. Int. J. Cancer 34:49-56(1984) DOI=10.1007/978-1-4612-0411-4_28 Williams A.C., Manning A., Harper S.J., Paraskeva C. Multiple steps in the in vitro immortalisation and neoplastic conversion of human colonic epithelial cells. (In book chapter) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim J.S., Dritschilo A. (eds.); pp.281-290; Humana Press; New York; USA (1990) PubMed=2253215 Baker S.J., Preisinger A.C., Jessup J.M., Paraskeva C., Markowitz S.D., Willson J.K.V., Hamilton S.R., Vogelstein B. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res. 50:7717-7722(1990) PubMed=2369746 Williams A.C., Harper S.J., Paraskeva C. Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence. Cancer Res. 50:4724-4730(1990) |
Cross-references |
Encyclopedic resources |
Wikidata; Q54938513
|
Polymorphism and mutation databases |
IARC_TP53; 23785
|
Entry history |
Entry creation | 06-Jun-2012 |
Last entry update | 19-Dec-2024 |
Version number | 12 |
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