ID   TTC-442
AC   CVCL_B255
SY   TTC442; TC-442; TU-442; A91
DR   Cell_Model_Passport; SIDM01458
DR   Cosmic; 802050
DR   DepMap; ACH-001750
DR   PRIDE; PXD039480
DR   Wikidata; Q54973233
RX   CelloPub=CLPUB00569;
RX   PubMed=7882340;
RX   PubMed=10602515;
RX   PubMed=19887553;
RX   PubMed=23665679;
RX   PubMed=23882450;
RX   PubMed=28196595;
RX   PubMed=36768928;
WW   https://tcpaportal.org/mclp/
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: MD Anderson Cell Lines Project.
CC   Omics: Cell surface proteome.
CC   Omics: Deep exome analysis.
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
ST   Source(s): COG
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 11,12
ST   D16S539: 11,14
ST   D18S51: 15,24
ST   D19S433: 13,16.2
ST   D21S11: 29
ST   D2S1338: 20,21
ST   D3S1358: 16,18
ST   D5S818: 10,11
ST   D7S820: 10,13
ST   D8S1179: 11,14
ST   FGA: 27
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 14,17
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   10Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 02-05-24; Version: 20
//
RX   CelloPub=CLPUB00569;
RA   Dickman P.S., Tsokos M.G., Triche T.J.;
RT   "Biology of rhabdomyosarcoma: cell culture, xenografts, and animal
RT   models.";
RL   (In) Rhabdomyosarcoma and related tumors in children and adolescents; Maurer H.M., Ruymann F.B., Pochedly C.E. (eds.); pp.49-88; CRC Press; Boca Raton (1991).
//
RX   PubMed=7882340;
RA   Sorensen P.H.B., Shimada H., Liu X.F., Lim J.F., Thomas G.,
RA   Triche T.J.;
RT   "Biphenotypic sarcomas with myogenic and neural differentiation
RT   express the Ewing's sarcoma EWS/FLI1 fusion gene.";
RL   Cancer Res. 55:1385-1392(1995).
//
RX   PubMed=10602515; DOI=10.1038/sj.onc.1203168;
RA   DeCristofaro M.F., Betz B.L., Wang W.-D., Weissman B.E.;
RT   "Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and
RT   primary rhabdomyosarcomas but not Wilms' tumors.";
RL   Oncogene 18:7559-7565(1999).
//
RX   PubMed=19887553; DOI=10.1158/1535-7163.MCT-09-0365;
RA   Hu K.-J., Lee C., Qiu D.-X., Fotovati A., Davies A., Abu-Ali S.,
RA   Wai D.H., Lawlor E.R., Triche T.J., Pallen C.J., Dunn S.E.;
RT   "Small interfering RNA library screen of human kinases and
RT   phosphatases identifies polo-like kinase 1 as a promising new target
RT   for the treatment of pediatric rhabdomyosarcomas.";
RL   Mol. Cancer Ther. 8:3024-3035(2009).
//
RX   PubMed=23665679; DOI=10.1038/onc.2013.129;
RA   Sokolowski E., Turina C.B., Kikuchi K., Langenau D.M., Keller C.;
RT   "Proof-of-concept rare cancers in drug development: the case for
RT   rhabdomyosarcoma.";
RL   Oncogene 33:1877-1889(2014).
//
RX   PubMed=23882450; DOI=10.3389/fonc.2013.00183;
RA   Hinson A.R.P., Jones R., Crose L.E.S., Belyea B.C., Barr F.G.,
RA   Linardic C.M.;
RT   "Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research:
RT   utility and pitfalls.";
RL   Front. Oncol. 3:183.1-183.12(2013).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=36768928; DOI=10.3390/ijms24032601;
RA   Timpanaro A., Piccand C., Uldry A.-C., Bode P.-K., Dzhumashev D.,
RA   Sala R., Heller M., Rossler J., Bernasconi M.;
RT   "Surfaceome profiling of cell lines and patient-derived xenografts
RT   confirm FGFR4, NCAM1, CD276, and highlight AGRL2, JAM3, and L1CAM as
RT   surface targets for rhabdomyosarcoma.";
RL   Int. J. Mol. Sci. 24:2601.1-2601.28(2023).
//