Cellosaurus logo
expasy logo

Cellosaurus HUES 66 (CVCL_B201)

[Text version]
Cell line name HUES 66
Synonyms HUES66
Accession CVCL_B201
Resource Identification Initiative To cite this cell line use: HUES 66 (RRID:CVCL_B201)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0057.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_YC46 (NYGCe001-A)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798

Markers:
AmelogeninX
CSF1PO11,12
D2S133820,23
D3S135817
D5S8189,11
D7S82011,12
D8S117911,14
D13S31712
D16S53911,12
D18S5115
D19S43314,15
D21S1131.2,32.2
FGA21,23
TH016,7
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001; PMCID=PMC3335201
Chen A.E., Egli D.M., Niakan K.K., Deng J., Akutsu H., Yamaki M., Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=21295703; DOI=10.1016/j.cell.2010.12.032; PMCID=PMC3063454
Bock C., Kiskinis E., Verstappen G., Gu H.-C., Boulting G.L., Smith Z.D., Ziller M.J., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K.C., Meissner A.
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell 144:439-452(2011)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-10-0057
SKIP; SKIP001553
Biological sample resources ENCODE; ENCBS032OHT
Encyclopedic resources Wikidata; Q54896806
Experimental variables resources EFO; EFO_0007092
Gene expression databases GEO; GSM621592
GEO; GSM637774
GEO; GSM670049
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number22