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Cellosaurus Abcam A-549 TGM2 KO 1 (CVCL_B1I0)

[Text version]
Cell line name Abcam A-549 TGM2 KO 1
Synonyms Human TGM2 (Transglutaminase 2) knockout A549
Accession CVCL_B1I0
Resource Identification Initiative To cite this cell line use: Abcam A-549 TGM2 KO 1 (RRID:CVCL_B1I0)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11778; TGM2.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=39220380; DOI=10.12688/f1000research.150684.2; PMCID=PMC11362715
Ayoubi R., Fotouhi M., Alende C., Gonzalez Bolivar S., Southern K., Laflamme C.
ABIF Consortium
NeuroSGC/YCharOS/EDDU Collaborative Group
A guide to selecting high-performing antibodies for protein-glutamine gamma-glutamyltransferase 2 (TGM2) for use in western blot, immunoprecipitation and immunofluorescence.
F1000Research 13:481.1-481.19(2024)

Cross-references
Cell line collections (Providers) Abcam; ab261876
Cell line databases/resources cancercelllines; CVCL_B1I0
Encyclopedic resources Wikidata; Q110430327
Entry history
Entry creation16-Dec-2021
Last entry update10-Apr-2025
Version number7