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Cellosaurus HUES 63 (CVCL_B198)

[Text version]
Cell line name HUES 63
Synonyms HUES63
Accession CVCL_B198
Resource Identification Initiative To cite this cell line use: HUES 63 (RRID:CVCL_B198)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0066.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Donor information: Embryo is sibling to those giving rise to HUES 62 (Cellosaurus=CVCL_B197) and HUES 64 (Cellosaurus=CVCL_B199).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798

Markers:
AmelogeninX,Y
CSF1PO9,12
D2S133818,20
D3S135815,16,20
D5S81811
D7S82010,12
D8S117913
D16S53912,13
D19S43313
D21S1131,31.2
FGA22,24
TH016,9
TPOX8,11
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001; PMCID=PMC3335201
Chen A.E., Egli D.M., Niakan K.K., Deng J., Akutsu H., Yamaki M., Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=21295703; DOI=10.1016/j.cell.2010.12.032; PMCID=PMC3063454
Bock C., Kiskinis E., Verstappen G., Gu H.-C., Boulting G.L., Smith Z.D., Ziller M.J., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K.C., Meissner A.
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell 144:439-452(2011)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-10-0066
SKIP; SKIP001544
Biological sample resources ENCODE; ENCBS301DIL
Encyclopedic resources Wikidata; Q54896802
Experimental variables resources EFO; EFO_0007088
Gene expression databases GEO; GSM621591
GEO; GSM637771
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number23