ID   UOK151
AC   CVCL_B126
SY   UOK-151; UOK 151
DR   cancercelllines; CVCL_B126
DR   Cosmic; 972875
DR   Cosmic; 972904
DR   Wikidata; Q54991381
RX   PubMed=7915601;
RX   PubMed=8493574;
RX   PubMed=9255309;
CC   Sequence variation: Mutation; HGNC; HGNC:12687; VHL; Simple; p.Ser183Ter (c.548C>A); ClinVar=VCV000002215; Zygosity=Unspecified (PubMed=7915601; PubMed=8493574).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C9385; Renal cell carcinoma
DI   ORDO; Orphanet_217071; Renal cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 15
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RX   PubMed=7915601; DOI=10.1038/ng0594-85;
RA   Gnarra J.R., Tory K., Weng Y.-K., Schmidt L.S., Wei M.H., Li H., Latif F.,
RA   Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.-S.R., Florence C.,
RA   Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H.,
RA   Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B.,
RA   Linehan W.M.;
RT   "Mutations of the VHL tumour suppressor gene in renal carcinoma.";
RL   Nat. Genet. 7:85-90(1994).
//
RX   PubMed=8493574; DOI=10.1126/science.8493574;
RA   Latif F., Tory K., Gnarra J.R., Yao M., Duh F.-M., Orcutt M.L.,
RA   Stackhouse T., Kuzmin I.A., Modi W., Geil L., Schmidt L.S., Zhou F.-W.,
RA   Li H., Wei M.H., Chen F., Glenn G., Choyke P., Walther M.M., Weng Y.-K.,
RA   Duan D.-S.R., Dean M., Glavac D., Richards F.M., Crossey P.A.,
RA   Ferguson-Smith M.A., Le Paslier D., Chumakov I., Cohen D.,
RA   Chinault A.C., Maher E.R., Linehan W.M., Zbar B., Lerman M.I.;
RT   "Identification of the von Hippel-Lindau disease tumor suppressor
RT   gene.";
RL   Science 260:1317-1320(1993).
//
RX   PubMed=9255309; DOI=10.1016/S0090-4295(97)00220-3;
RA   Walther M.M., Kleiner D.E., Lubensky I.A., Pozzatti R., Nyguen T.,
RA   Gnarra J.R., Hurley K., Venzon D., Linehan W.M.,
RA   Stetler-Stevenson W.G.;
RT   "Progelatinase A mRNA expression in cell lines derived from tumors in
RT   patients with metastatic renal cell carcinoma correlates inversely
RT   with survival.";
RL   Urology 50:295-301(1997).
//