ID   UOK139
AC   CVCL_B118
SY   UOK-139; UOK 139
DR   Cosmic; 972899
DR   Wikidata; Q54991370
RX   PubMed=7915601;
RX   PubMed=8319216;
RX   PubMed=9255309;
CC   Sequence variation: Mutation; HGNC; HGNC:12687; VHL; Simple; p.Thr157Leufs*2 (c.469delA); Zygosity=Unspecified (PubMed=7915601).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 13
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RX   PubMed=7915601; DOI=10.1038/ng0594-85;
RA   Gnarra J.R., Tory K., Weng Y.-K., Schmidt L.S., Wei M.H., Li H., Latif F.,
RA   Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.-S.R., Florence C.,
RA   Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H.,
RA   Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B.,
RA   Linehan W.M.;
RT   "Mutations of the VHL tumour suppressor gene in renal carcinoma.";
RL   Nat. Genet. 7:85-90(1994).
//
RX   PubMed=8319216;
RA   Reiter R.E., Anglard P., Liu S., Gnarra J.R., Linehan W.M.;
RT   "Chromosome 17p deletions and p53 mutations in renal cell carcinoma.";
RL   Cancer Res. 53:3092-3097(1993).
//
RX   PubMed=9255309; DOI=10.1016/S0090-4295(97)00220-3;
RA   Walther M.M., Kleiner D.E., Lubensky I.A., Pozzatti R., Nyguen T.,
RA   Gnarra J.R., Hurley K., Venzon D., Linehan W.M.,
RA   Stetler-Stevenson W.G.;
RT   "Progelatinase A mRNA expression in cell lines derived from tumors in
RT   patients with metastatic renal cell carcinoma correlates inversely
RT   with survival.";
RL   Urology 50:295-301(1997).
//