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Cellosaurus Abcam Hep-G2 LRP6 KO (CVCL_B0ZM)

[Text version]
Cell line name Abcam Hep-G2 LRP6 KO
Synonyms Human LRP6 knockout Hep G2
Accession CVCL_B0ZM
Resource Identification Initiative To cite this cell line use: Abcam Hep-G2 LRP6 KO (RRID:CVCL_B0ZM)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 6698; LRP6.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Abcam; ab277909
Cell line databases/resources cancercelllines; CVCL_B0ZM
Encyclopedic resources Wikidata; Q110432487
Entry history
Entry creation16-Dec-2021
Last entry update05-Oct-2023
Version number5