ID   293T/ACE2 [Japan 2021]
AC   CVCL_B0XR
DR   Wikidata; Q108819503
RX   PubMed=33686154;
CC   Group: SARS-CoV-2 research cell line.
CC   Virology: Highly susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33686154).
CC   Transfected with: HGNC; 13557; ACE2.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=tsA].
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0063 ! HEK293T
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 23-09-21; Last updated: 05-10-23; Version: 6
//
RX   PubMed=33686154; DOI=10.1038/s41598-021-84882-7;
RA   Uemura K., Sasaki M., Sanaki T., Toba S., Takahashi Y., Orba Y.,
RA   Hall W.W., Maenaka K., Sawa H., Sato A.;
RT   "MRC5 cells engineered to express ACE2 serve as a model system for the
RT   discovery of antivirals targeting SARS-CoV-2.";
RL   Sci. Rep. 11:5376-5376(2021).
//