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Cellosaurus HEK293-FT APEX1 KO clone 2A9 (CVCL_B0WB)

[Text version]
Cell line name HEK293-FT APEX1 KO clone 2A9
Synonyms 2A9
Accession CVCL_B0WB
Resource Identification Initiative To cite this cell line use: HEK293-FT APEX1 KO clone 2A9 (RRID:CVCL_B0WB)
Comments Doubling time: 19.4 hours (PubMed=34529719).
Knockout cell: Method=CRISPR/Cas9; HGNC; 587; APEX1.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6911 (HEK293-FT)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=34529719; DOI=10.1371/journal.pone.0257473; PMCID=PMC8445474
Kim D.V., Kulishova L.M., Torgasheva N.A., Melentyev V.S., Dianov G.L., Medvedev S.P., Zakian S.M., Zharkov D.O.
Mild phenotype of knockouts of the major apurinic/apyrimidinic endonuclease APEX1 in a non-cancer human cell line.
PLoS ONE 16:E0257473-E0257473(2021)

Cross-references
Encyclopedic resources Wikidata; Q108820445
Entry history
Entry creation23-Sep-2021
Last entry update29-Jun-2023
Version number4