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Cellosaurus 3C5 [Mouse hybridoma against human PSCA] (CVCL_B0TR)

[Text version]
Cell line name 3C5 [Mouse hybridoma against human PSCA]
Accession CVCL_B0TR
Resource Identification Initiative To cite this cell line use: 3C5 [Mouse hybridoma against human PSCA] (RRID:CVCL_B0TR)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-12616.
Monoclonal antibody isotype: IgG2a, kappa.
Monoclonal antibody target: UniProtKB; O43653; Human PSCA.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_D145 (HL-1 Friendly Myeloma-653)
Category Hybridoma
Publications

PubMed=10713670; DOI=10.1038/sj.onc.1203426
Gu Z.-N., Thomas G., Yamashiro J., Shintaku I.P., Dorey F., Raitano A.B., Witte O.N., Said J.W., Loda M., Reiter R.E.
Prostate stem cell antigen (PSCA) expression increases with high Gleason score, advanced stage and bone metastasis in prostate cancer.
Oncogene 19:1288-1296(2000)

PubMed=11226295; DOI=10.1073/pnas.051624698; PMCID=PMC30194
Saffran D.C., Raitano A.B., Hubert R.S., Witte O.N., Reiter R.E., Jakobovits A.
Anti-PSCA mAbs inhibit tumor growth and metastasis formation and prolong the survival of mice bearing human prostate cancer xenografts.
Proc. Natl. Acad. Sci. U.S.A. 98:2658-2663(2001)

Patent=US8524460
Reiter R.E., Witte O.N.
PSCA: prostate stem cell antigen and uses thereof.
Patent number US8524460, 03-Sep-2013

Cross-references
Encyclopedic resources Wikidata; Q108819587
Entry history
Entry creation23-Sep-2021
Last entry update21-Mar-2023
Version number3