Cellosaurus cell line LB45-LUDSN11 (CVCL

Cross-references
Cell line name	LB45-LUDSN11
Accession	CVCL_B0GZ
Resource Identification Initiative	To cite this cell line use: LB45-LUDSN11 (RRID:CVCL_B0GZ)
Comments	Doubling time: 21 hours (PubMed=10397714). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:12591; UROD. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:12591; UROD; Simple; p.Gly281Glu (c.842G>A); ClinVar=VCV000000066; Zygosity=Homozygous (PubMed=10397714).
Disease	Hepatoerythropoietic porphyria (NCIt: C84754) Hepatoerythropoietic porphyria (ORDO: Orphanet_95159)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_B0GY (LB45)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=10397714; DOI=10.1182/blood.V94.2.465 Fontanellas A., Mazurier F., Moreau-Gaudry F., Belloc F., Ged C., de Verneuil H. Correction of uroporphyrinogen decarboxylase deficiency (hepatoerythropoietic porphyria) in Epstein-Barr virus-transformed B-cell lines by retrovirus-mediated gene transfer: fluorescence-based selection of transduced cells. Blood 94:465-474(1999)
Encyclopedic resources	Wikidata; Q108820672
Entry history
Entry creation	23-Sep-2021
Last entry update	19-Dec-2024
Version number	6