ID   ZOSL-1
AC   CVCL_B0F2
DR   CCRID; 4201PAT-CCTCC01643
DR   Wikidata; Q108821566
RX   Patent=CN112080473B;
RX   PubMed=34221892;
CC   Group: Patented cell line.
CC   Problematic cell line: Probably contaminated. The STR profile is identical to that of the HOS cell line. Originally thought to originate from the lung metastasis of a 12 year old female Chinese osteosarcoma patient.
CC   Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C202088.
CC   Population: Caucasian.
CC   Doubling time: 39.28 +- 3.04 hours (Patent=CN112080473B; PubMed=34221892).
CC   Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
ST   Source(s): Patent=CN112080473B; PubMed=34221892
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D12S391: 20
ST   D13S317: 12
ST   D16S539: 10,13
ST   D18S51: 14
ST   D19S433: 13
ST   D21S11: 31.2,32.2
ST   D2S1338: 24,25
ST   D2S441: 10
ST   D3S1358: 15
ST   D5S818: 13
ST   D6S1043: 18
ST   D7S820: 11,12
ST   D8S1179: 13,14
ST   FGA: 24
ST   Penta D: 9,10
ST   Penta E: 7,12
ST   TH01: 6
ST   TPOX: 8,11
ST   vWA: 17,18
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0312 ! HOS
SX   Female
AG   13Y
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 29-06-23; Version: 5
//
RX   Patent=CN112080473B;
RA   Yin, Jun-Qiang
RA   Shen, Jing-Nan
RA   Zhao, Ju-Peng
RA   Fan, Ze-Pei
RT   "Primary cell line of osteosarcoma lung metastasis range and culture
RT   method and application thereof.";
RL   Patent number CN112080473B, 03-Jun-2022.
//
RX   PubMed=34221892; DOI=10.1016/j.jbo.2021.100378; PMCID=PMC8243521;
RA   Fan, Ze-Pei
RA   Huang, Guan-Yu
RA   Zhao, Ju-Peng
RA   Li, Wu-Guo
RA   Lin, Tiao
RA   Su, Qiao
RA   Yin, Jun-Qiang
RA   Shen, Jing-Nan
RT   "Establishment and characterization of a highly metastatic human
RT   osteosarcoma cell line from osteosarcoma lung metastases.";
RL   J. Bone Oncol. 29:100378.1-100378.9(2021).
//