ID   2C7 [Mouse hybridoma against N.gonorrhoease LOS]
AC   CVCL_B0E6
DR   Wikidata; Q108819515
RX   Patent=US6099839;
RX   PubMed=2428752;
RX   PubMed=10593954;
RX   PubMed=11878767;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-11859.
CC   Monoclonal antibody isotype: IgG3, lambda.
CC   Monoclonal antibody target: Neisseria gonorrhoeae lipo-oligosaccharide (LOS) (Note=Binds to the inner 15253 LOS structure found within WG LOS).
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_2199 ! Sp2/0-Ag14
CA   Hybridoma
DT   Created: 23-09-21; Last updated: 21-03-23; Version: 4
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RX   Patent=US6099839;
RA   Rice P.A., Gulati S., McQuillen D.P.;
RT   "Gonococcal anti-idiotypic antibodies and methods compositions using
RT   them.";
RL   Patent number US6099839, 08-Aug-2000.
//
RX   PubMed=2428752; DOI=10.1128/IAI.54.1.63-69.1986;
RA   Mandrell R., Schneider H., Apicella M.A., Zollinger W., Rice P.A.,
RA   Griffiss J.M.;
RT   "Antigenic and physical diversity of Neisseria gonorrhoeae
RT   lipooligosaccharides.";
RL   Infect. Immun. 54:63-69(1986).
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RX   PubMed=10593954; DOI=10.1074/jbc.274.51.36550;
RA   Yamasaki R., Koshino H., Kurono S., Nishinaka Y., McQuillen D.P.,
RA   Kume A., Gulati S., Rice P.A.;
RT   "Structural and immunochemical characterization of a Neisseria
RT   gonorrhoeae epitope defined by a monoclonal antibody 2C7; the antibody
RT   recognizes a conserved epitope on specific lipo-oligosaccharides in
RT   spite of the presence of human carbohydrate epitopes.";
RL   J. Biol. Chem. 274:36550-36558(1999).
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RX   PubMed=11878767; DOI=10.3109/08830180109043036;
RA   Gulati S., Ngampasutadol J., Yamasaki R., McQuillen D.P., Rice P.A.;
RT   "Strategies for mimicking Neisserial saccharide epitopes as
RT   vaccines.";
RL   Int. Rev. Immunol. 20:229-250(2001).
//