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Cellosaurus PC3-EMT1 (CVCL_B0CN)

[Text version]
Cell line name PC3-EMT1
Accession CVCL_B0CN
Resource Identification Initiative To cite this cell line use: PC3-EMT1 (RRID:CVCL_B0CN)
Comments Population: Caucasian.
Characteristics: Selected from a mesenchymal sub-population of the parent cell line.
Characteristics: Transfected with a pLentilox-EV-Luc luciferase expression vector.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B0CB (PC3-epi)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=24124593; DOI=10.1371/journal.pone.0076773; PMCID=PMC3790720
Roca H., Hernandez J.R., Weidner S., McEachin R.C., Fuller D., Sud S., Schumann T., Wilkinson J.E., Zaslavsky A., Li H.-W., Maher C.A., Daignault-Newton S., Healy P.N., Pienta K.J.
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer.
PLoS ONE 8:E76773-E76773(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B0CN
Encyclopedic resources Wikidata; Q108821090
Gene expression databases GEO; GSM1063982
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number8